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Genetic inheritance - part two - EdexcelSex determination

We inherit our sex (male or female) and blood group from our parents. Genetic disorders can also be inherited. Selective breeding occurs when humans breed plants and animals for specific characteristics. Cloning (often in plants and not in humans) makes genetically identical copies of the one parent organism.

Part of Biology (Single Science)Genetics

Sex determination

Inheritance of biological sex

Diploid human body cells have 23 pairs of in the nucleus. Twenty two pairs are known as , and control characteristics, but the 23rd pair carries genes that determine sex and are known as the sex chromosomes.

  • males have two different sex chromosomes, X Y
  • females have two X chromosomes, XX.

Chromosomes from a male

These diagrams are known as human karyotypes, and show all the chromosomes aligned in pairs.

Chromosomes from a male, since it contains a Y chromosome

The blue box shows the two sex chromosomes - these are different sizes, therefore an X (larger chromosome) and a Y (smaller one).

Chromosomes from a female

The red box shows the two sex chromosomes 鈥 these are the same size, both two X larger chromosomes.

Females have two X chromosomes

Genetic diagrams

A genetic diagram, like a Punnett square, shows how may combine in . The diagram below shows how sex is inherited.

Diagram showing how genes are inherited
Figure caption,
The female alleles are XX and the male alleles are XY

The two possible combinations are:

  • an X from the mother and an X chromosome from the father - producing a girl (female phenotype from the XX )
  • an X chromosome from the mother and a Y chromosome from the father - producing a boy (male phenotype from the XY phenotype).

All ova have an X chromosome. Half of sperm have an X chromosome and half have a Y.

Because of this the ratio of female to male offspring is 1:1. On average, half of the offspring will be girls and half will be boys. This can also be converted into a of 50% (XX) and 50% (XY).