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The doctor spends time with the D'Arcy family in Shropshire. Mum and dad Dottie and Russ have a love of fast food and shock the doctor with a regular family meal. Dotti discovers she has type 2 diabetes, and Dr Rangan's mission to correct her diet leads him to unravel the root cause of the family's relationship with food.

Rangan discovers that Russ's firefighter career is more deskbound than active, so encourages a radical lifestyle change. The whole family's health is interlinked, and the doctor encourages them to transform their health by making simple lifestyle changes - involving every aspect from the moment they wake up to the way they sleep at night.

At the end of his intervention, the family undergo a series of tests to measure just how much impact the doctor's suggested lifestyle changes have had on their health, with incredible results.